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cff-version: 1.2.0
message: 'To cite package "AHTauDesign" in publications use:'
type: software
license: GPL-3.0-only
title: 'AHTauDesign: Truncation Time Selection for Average Hazard Analyses'
version: 0.1.0
doi: 10.32614/CRAN.package.AHTauDesign
abstract: Implements a two-stage, design-informed framework for selecting the truncation
  time in time-to-event trials analyzed with the average hazard estimand, motivated
  by pediatric oncology settings with small samples, slow accrual, and limited follow-up.
  Stage 1 validates a clinically proposed truncation time against the planned design
  using simulation-based diagnostics for risk-set support, follow-up coverage, estimability,
  and estimator stability, classifying it as Pass, Borderline, or Fail. Stage 2 performs
  constrained optimization over a grid of candidate truncation times within a clinical-distance
  window, maximizing a utility subject to feasibility constraints, with an independent
  evaluation run to assess the selected time. Supports proportional-hazards, early-,
  and delayed-effect patterns, uniform accrual with administrative censoring, and
  calibrated exponential random censoring.
authors:
- family-names: Zhao
  given-names: Xinyue
  email: xinyuezhao27@gwu.edu
- family-names: Pan
  given-names: Haitao
  email: Haitao.Pan@STJUDE.ORG
repository: https://xyzhao27.r-universe.dev
commit: 9ac9ae672b36e3f267afc2023216fa0a6ae25e1a
date-released: '2026-09-10'
contact:
- family-names: Zhao
  given-names: Xinyue
  email: xinyuezhao27@gwu.edu