https://xyzhao27.r-universe.devRecent package updates in xyzhao27R-universehttps://github.com/xyzhao27.pnghttps://xyzhao27.r-universe.devThu, 10 Sep 2026 08:40:08 GMTxinyuezhao27@gwu.edu (Xinyue Zhao)Implements a two-stage, design-informed framework for selecting the truncation time in time-to-event trials analyzed with the average hazard estimand, motivated by pediatric oncology settings with small samples, slow accrual, and limited follow-up. Stage 1 validates a clinically proposed truncation time against the planned design using simulation-based diagnostics for risk-set support, follow-up coverage, estimability, and estimator stability, classifying it as Pass, Borderline, or Fail. Stage 2 performs constrained optimization over a grid of candidate truncation times within a clinical-distance window, maximizing a utility subject to feasibility constraints, with an independent evaluation run to assess the selected time. Supports proportional-hazards, early-, and delayed-effect patterns, uniform accrual with administrative censoring, and calibrated exponential random censoring.https://github.com/r-universe/xyzhao27/actions/runs/38130807111Thu, 10 Sep 2026 08:40:08 GMTAHTauDesign0.1.0successhttps://xyzhao27.r-universe.devhttps://github.com/cran/AHTauDesignAHTauDesign.RmdAHTauDesign.htmlDesign-informed truncation time selection2026-09-10 08:40:082026-09-10 08:40:08